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      Anti-Na+/K+-ATPase Alpha antibody[STJ99661]
      • Anti-Na+/K+-ATPase Alpha antibody[STJ99661]

      Anti-Na+/K+-ATPase Alpha antibody[STJ99661]

      Product nameAnti-Na+/K+-ATPase Alpha antibodyShort DescriptionRabbit polyclonal against Na+/K+-ATPase alphaDescriptionRabbit

      • 宿主:Rabbit
      • 克隆性:polyclonal
      • 種屬:Human, Mouse, Rat
      • 應用:ELISA, WB
      • 規格:Trial 50ul 100ul 200ul
      • 聯系:錢女士 15301726783
      標簽:
      Product nameAnti-Na+/K+-ATPase Alpha antibody
      Short DescriptionRabbit polyclonal against Na+/K+-ATPase alpha
      DescriptionRabbit polyclonal to Na+/K+-ATPase alpha1.
      ApplicationsELISA, WB
      Dilution rangeWB 1:500-2000
      ELISA 1:10000-20000
      SpecificityThis antibody detects endogenous levels of Na+/K+-ATPase ?±1.
      Protein NameSodium/Potassium-Transporting Atpase Subunit Alpha-1
      Na(+/K(+ Atpase Alpha-1 Subunit
      Sodium Pump Subunit Alpha-1
      ImmunogenSynthesized peptide derived from human Na+/K+-ATPase alpha1.
      Storage InstructionStore at-20°C, and avoid repeat freeze-thaw cycles.
      NoteFOR RESEARCH USE ONLY (RUO).
      HostRabbit
      ClonalityPolyclonal
      ReactivityHuman, Mouse, Rat
      ConjugationUnconjugated
      Concentration1 mg/ml
      PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      IsotypeIgG
      FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      Gene ID476
      Gene SymbolATP1A1
      Molecular Weight130 kDa
      Database LinksHGNC:799
      OMIM:182310
      Alternative NamesAnti-Sodium/Potassium-Transporting Atpase Subunit Alpha-1 antibody
      Anti-Na(+/K(+ Atpase Alpha-1 Subunit antibody
      Anti-Sodium Pump Subunit Alpha-1 antibody
      Anti-ATP1A1 antibody
      FunctionThis is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
      Post-translational ModificationsPhosphorylation on Tyr-10 modulates pumping activity. Phosphorylation of Ser-943 by PKA modulates the response of ATP1A1 to PKC. Dephosphorylation by protein phosphatase 2A (PP2A) following increases in intracellular sodium, leading to increase catalytic activity.
      Cellular LocalizationCell Membrane
      Sarcolemma
      Multi-Pass Membrane Protein
      Melanosome
      Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
      Swiss-Prot KeyAT1A1_HUMAN

      Anti-Na+/K+-ATPase Alpha antibody[STJ99661](圖1)

       
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