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      Anti-IL-6 antibody[STJ96713]
      • Anti-IL-6 antibody[STJ96713]
      • Anti-IL-6 antibody[STJ96713]
      • Anti-IL-6 antibody[STJ96713]

      Anti-IL-6 antibody[STJ96713]

      Product nameAnti-IL-6 antibodyShort DescriptionRabbit polyclonal against IL-6DescriptionIL-6 is a protein encoded by the IL6

      • 宿主:Rabbit
      • 克隆性:Polyclonal
      • 種屬:Human
      • 應用:ELISA, IHC-p, WB
      • 規格:20ul,50ul,100ul,200ul
      • 聯系:錢女士 15301726783
      標簽:
      Product nameAnti-IL-6 antibody[STJ96713]
      Short DescriptionRabbit polyclonal against IL-6
      DescriptionIL-6 is a protein encoded by the IL6 gene which is approximately 23, 7 kDa. IL-6 is secreted and is involved in apoptotic pathways in synovial fibroblasts, PEDF induced signalling, the GPCR Pathway, the TGF-Beta pathway and toll-like receptor signalling pathways. IL6 is a cytokine that functions in inflammation and the maturation of B cells. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor. IL-6 is expressed in the lung, blood, nervous system, bone marrow and the intestines. Mutations in the IL6 gene result in rheumatoid arthritis systemic juvenile and an inflammatory articular disorder. STJ96713 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of IL-6 protein.
      ApplicationsELISA, IHC-p, WB
      Dilution rangeWB 1:500-1:2000
      IHC-p 1:100-1:300
      ELISA 1:20000
      SpecificityIL-6 polyclonal antibody detects endogenous levels of IL-6 protein.
      Protein NameInterleukin-6
      Il-6
      B-Cell Stimulatory Factor 2
      Bsf-2
      Ctl Differentiation Factor
      Cdf
      Hybridoma Growth Factor
      Interferon Beta-2
      Ifn-Beta-2
      ImmunogenSynthesized peptide derived from human IL-6.
      Immunogen RegionInternal
      Storage InstructionStore at-20°C, and avoid repeat freeze-thaw cycles.
      NoteFOR RESEARCH USE ONLY (RUO).


      HostRabbit
      ClonalityPolyclonal
      ReactivityHuman
      ConjugationUnconjugated
      Concentration1 mg/ml
      PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      IsotypeIgG
      FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.


      Gene ID3569
      Gene SymbolIL6
      Molecular Weight25 kDa
      Database LinksHGNC:6018
      OMIM:147620
      Alternative NamesAnti-Interleukin-6 antibody
      Anti-Il-6 antibody
      Anti-B-Cell Stimulatory Factor 2 antibody
      Anti-Bsf-2 antibody
      Anti-Ctl Differentiation Factor antibody
      Anti-Cdf antibody
      Anti-Hybridoma Growth Factor antibody
      Anti-Interferon Beta-2 antibody
      Anti-Ifn-Beta-2 antibody
      Anti-IL6 IFNB2 antibody
      FunctionCytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
      Post-translational ModificationsN-and O-glycosylated.
      Cellular LocalizationSecreted
      Swiss-Prot KeyIL6_HUMAN

      Anti-IL-6 antibody[STJ96713](圖1)



       
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