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      Anti-COX4 antibody[STJ97368]
      • Anti-COX4 antibody[STJ97368]
      • Anti-COX4 antibody[STJ97368]

      Anti-COX4 antibody[STJ97368]

      Product nameAnti-COX4 antibodyShort DescriptionRabbit polyclonal against COX4DescriptionRabbit polyclonal to COX4.Application

      • 宿主:Rabbit
      • 克隆性:Polyclonal
      • 種屬:Human, Mouse, Rat
      • 應用:IHC-p, WB
      • 規格:20ul,50ul,100ul,200ul
      • 聯系:錢女士 15301726783
      標簽:
      Product nameAnti-COX4 antibody
      Short DescriptionRabbit polyclonal against COX4
      DescriptionRabbit polyclonal to COX4.
      ApplicationsIHC-p, WB
      Dilution rangeWB 1:1000
      IHC 1:500-1000
      SpecificityThe antibody detects endogenous COX4 protein.
      Protein NameCytochrome C Oxidase Subunit 4 Isoform 1-Mitochondrial
      Cytochrome C Oxidase Polypeptide Iv
      Cytochrome C Oxidase Subunit Iv Isoform 1
      Cox Iv-1
      ImmunogenRecombinant Protein
      Storage InstructionStore at-20°C, and avoid repeat freeze-thaw cycles.
      NoteFOR RESEARCH USE ONLY (RUO).
      HostRabbit
      ClonalityPolyclonal
      ReactivityHuman, Mouse, Rat
      ConjugationUnconjugated
      PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      IsotypeIgG
      FormulationPBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol.
      Gene ID1327
      Gene SymbolCOX4I1
      Database LinksHGNC:2265
      OMIM:123864
      Alternative NamesAnti-Cytochrome C Oxidase Subunit 4 Isoform 1-Mitochondrial antibody
      Anti-Cytochrome C Oxidase Polypeptide Iv antibody
      Anti-Cytochrome C Oxidase Subunit Iv Isoform 1 antibody
      Anti-Cox Iv-1 antibody
      Anti-COX4I1 COX4 antibody
      FunctionComponent of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunbit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
      Cellular LocalizationMitochondrion Inner Membrane
      Single-Pass Membrane Protein

      Anti-COX4 antibody[STJ97368](圖1)

       
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